What is RNFL

RNFL Analysis in the Diagnosis of Glaucoma - Glaucoma Toda

Average RNFL Thickness This number represents the average thickness across the Circular Tomogram. It provides an excellent representation of diffuse change. But be aware that small, and clinically significant, changes will not be reflected by this number RNFL Thickness Retinal nerve fiber layer thickness represents the ganglion cell axons before they enter the optic nerve. Loss of retinal nerve fiber layer can be observed in red-free photos and is quantified with OCT. The peripapillary RNFL thickness is by far the most popular OCT parameter used for glaucoma diagnosis and monitoring progression Optometry RNFL abbreviation meaning defined here. What does RNFL stand for in Optometry? Get the top RNFL abbreviation related to Optometry

Retinal Nerve Fiber Layer - an overview ScienceDirect Topic

Looking for the definition of RNFL? Find out what is the full meaning of RNFL on Abbreviations.com! 'Retinal Nerve Fiber Layer' is one option -- get in to view more @ The Web's largest and most authoritative acronyms and abbreviations resource Though the RNFL thickness is a key factor in tracking progression, physicians say it's often helpful to look at multiple structures, including macular thickness, especially in cases where the RNFL thickness may be indeterminate. Because any structure is subject to artifacts, it's better to have at least two structures to measure with. Average retinal nerve fiber layer thickness (micrometers) for 3 diagnostic groups. Diamonds represent 95% confidence intervals. Nerve fiber layer was significantly thinner in glaucomatous eyes than in ocular hypertensive eyes and was significantly thinner in ocular hypertensive eyes than in normal eyes (P<.05). Figure 2

Average RNFL thickness is suspicious at 84 microns OD and 85 microns OS. There is some asymmetry between the optic nerve areas and the superior temporal RNFL thinning with some sporadic areas of. About Press Copyright Contact us Creators Advertise Developers Terms Privacy Policy & Safety How YouTube works Test new features Press Copyright Contact us Creators.

Conventional testing images in a normal subject

Optic Nerve and Retinal Nerve Fiber Imaging - EyeWik

  1. Abstract Purpose: To compare the rates of circumpapillary retinal nerve fiber layer (RNFL) and macular retinal ganglion cell-inner plexiform layer (GCIPL) change over time in healthy and glaucoma eyes
  2. Rnfl is a thickness measurement of the tissue and not an absolute measure of the optic nerve. 4.2k views Answered >2 years ago. Thank. Dr. Douglas Liva answered. Ophthalmology 40 years experience. RNFL is thin: Then oct measures an individual retinal nerve fiber layer and compares it to normals your age. If 95% of normals have a thicker nerve.
  3. e normative values of retinal nerve fibre layer thickness (RNFL) and optic nerve head (ONH) parameters and their association with routine clinical tests such as refractive error (RE), stereoacuity (SA), and contrast sensitivity (CS) in an African population
  4. Here, we discuss the ramifications of red disease and overtreatment for patients with glaucoma. This series of RNFL scans over a three-year period demonstrates progressive RNFL thinning. The downward slope of the global optic nerve trend, on the right, indicates progressive loss of tissue, indicative of worsening disease
  5. The RNFL is the innermost lay of the retina and is comprised of the nerve fiber bundles that will compose the optic nerve. In multiple studies, researchers have demonstrated that RNFL loss occurs in the MS patients regardless of their disease subtype or history of optic neuritis
  6. What is RNFL meaning in Optic? 1 meaning of RNFL abbreviation related to Optic: Optic. Medical. Ophthalmology. Ophthalmic. Fiber. 1 / 5. Rating

Glaucoma is a group of many conditions sharing a final common pathway characterized by accelerated death of retinal ganglion cells and their retinal nerve fiber layer (RNFL) axons resulting in characteristic visual field defects and corresponding optic nerve head anatomical changes The Cirrus RNFL map represents a 6 x 6 mm cube of A-scan data centered over the optic nerve in which a 3.4 mm diameter circle of RNFL data is extracted to create what is referred to as the TSNIT map (temporal, superior, nasal, inferior, temporal) Optical coherence tomography (OCT) is a non-contact optical technique that allows imaging and measurement of the retinal nerve fiber layer (RNFL). Since 1991,1 OCT has undergone rapid evolution for use in detection and monitoring of glaucoma and macular diseases. Based on the principle of low-coherence interferometry, OCT measures the intensity of backscattered infrared light What does RNFL stand for? List of 12 RNFL definitions. Top RNFL abbreviation meanings updated March 202 For RNfL we have found 4 definitions.; What does RNFL mean? We know 4 definitions for RNFL abbreviation or acronym in 2 categories. Possible RNFL meaning as an acronym, abbreviation, shorthand or slang term vary from category to category. Please look for them carefully. RNFL Stands For: All acronyms (4) Airports & Locations Business & Finance Common Government & Military Medicine & Science (3.

RNFL analysis is an extremely helpful tool for the manage-ment of glaucoma patients. It can be used in conjunction with other examination findings and diagnostic imaging tools to diagnose early or preperimetric cases, and the quantitative nature of these measurements is useful fo Real nigga for life. These cookies are necessary for the website to function and cannot be switched off in our systems The retinal nerve fiber layer (RNFL) is composed of retinal ganglion cell axons, which form the optic nerve when bundled together. RNFL thins with aging, and the decreased thickness indicates retrograde degeneration of the retinal ganglion cell axons. There is also speculation that amyloid-β plaque deposits lead to neuroretinal atrophy

RNFL - What does RNFL stand for? The Free Dictionar

RNFL/retinal thickness and its correlation to age. The mean values of retinal or RNFL thickness are within the range already described in the literature. Schumann 5 for example found a retinal thickness of 235.5 μm and a RNFL thickness of 91.5 μm in the temporal parapapillary area. In the study he used a circular OCT scan around the optic. The Cirrus RNFL map represents a 6 x 6 mm cube of A-scan data centered over the optic nerve in which a 3.4 mm diameter circle of RNFL data is extracted to create what is referred to as the TSNIT map (temporal, superior, nasal, inferior, temporal) RNFL thickness is defined as the distance between ILM and outer interface of the inner most highly reflective layer presumably RNFL. GCC thickness is defined as the distance between ILM and the outer interface of the second inner highly reflective layer presumably the outer border of inner plexiform layer (IPL)

Conclusions: Optical coherence tomography can be used to measure RNFL thickness in children. Refraction had an effect on RNFL thickness. In normal children, variation in RNFL thickness is large. The normative data provided by this study may assist in identifying changes in RNFL thickness in children The decrease in RNFL is thought to continue for 6 months following ON onset. 5. Visual evoked potentials (VEPs) can also provide valuable information regarding optic nerve impairment in ON. VEPs evaluate optic nerve function by calculating P100 latency and amplitude, which are generally abnormal in the setting of acute and remote optic neuritis The mean RNFL thickness was statistically higher in the study group than in the control group in all quadrants and in the 360° mean measurement . In addition to RNFL thickening, peripapillary circular OCT scans showed a hyporeflective space above the retinal pigment epithelium (Figure 2, A) The normative database for RNFL and macular thickness was developed by CZM to provide comparative information for assessing patients. 20 Seven centers participated in the prospective, nonrandomized, multicenter study to develop the Cirrus RNFL and macula normative databases and involved 284 subjects with an age range of 18 to 84 years, with a.

Average RNFL Thickness Ranges ~ 75 -110 microns The Anatomy of the RNFL Printout 34 There is a Large Range of Normal • Just like perimetry, the average patient can lose a third of his/her RNFL or neuro-retinal rim and still be inside the normal range. 50th percentile = 89 microns 5thpercentile = 75 microns 95th percentile = 107 micron The thin RNFL in the right eye is clearly visible in the OCT image (figure 4 - OD white arrow). The left eye shows significant loss of the temporal RNFL, consistent with severe glaucomatous damage (figures 4, 5 & 6 - OS white/black arrows). Figure 4 RNFL OCT scans Figure 5 RNFL thickness profiles Figure 6 RNFL classification101 charts Figure Myelinated retinal nerve fiber layers (MRNF) are retinal nerve fibers anterior to the lamina cribrosa that, unlike normal retinal nerve fibers, have a myelin sheath. Clinically, they appear to be gray-white well-demarcated patches with frayed borders on the anterior surface of the neurosensory retina.[1][2] MNFL are present in 0.57 to 1% of the population and can occur bilaterally in. If you think you crew can beat my squad add hollabakkid but be warned when we win your crew will be my next victims on my channelGRAND THEFT AUTO Vhttps://st.. Backgrounds: Abnormal retinal nerve fiber layer (RNFL) thickness has been observed in patients with Alzheimer's disease (AD) and therefore suggested to be a potential biomarker of AD. However, whether the changes in RNFL thickness are associated with the atrophy of brain structure volumes remains unknown. We, therefore, set out a prospective investigation to determine the association between.

When analyzing RNFL sectors, the threshold to demonstrate clinically significant change is approximately 7 µm to 8 µm for the temporal, superior, inferior, and nasal sectors. 7 A change >10 µm is more likely to be clinically significant when comparing scans of the RNFL subsectors, such as superotemporal or inferotemporal. These subsectors. Rnfl Savo is on Facebook. Join Facebook to connect with Rnfl Savo and others you may know. Facebook gives people the power to share and makes the world more open and connected The RNFL thickness profile (TSNIT) also shows confirmed inferior progression. Click image to enlarge. Glaucoma Progression. Detecting progressive changes in glaucoma is an important, yet difficult, aspect of disease management. Progression detection is challenging for a variety of reasons, including: the slow but variable rate of progression. Rapid RNFL thinning during an initial follow-up period was significantly predictive of concurrent and subsequent rates of visual field decline over an extended period, the study authors wrote the RNFL thickness as the distance between the viteror-etinal interface and the posterior border of the RNFL.32 A real-time TruTrack Active EyeTracking system links the confocal scanning laser ophthalmoscopy and SD-OCT portions of the device. This TruTrack appears to be asso

RNFL/optic disc cube scan and see some diffuse dropout.) This is where an expert in glaucoma diagnosis and manage-ment shines. A lot depends on the location and characteristics of the RNFL defi cit. STRUCTURE & FUNCTION Dr. Dunbar: A paper by Mederios and colleagues shows how RNFL defects progress1, and what struck me in this study was that. Ganglion cell layer (GCL) is composed of cell bodies of retinal ganglion cells Retinal nerve fiber layer (RNFL) is formed by axons of the retinal ganglion cells Inner plexiform layer (IPL) consists of axons of bipolar and amacrine cells and dendrites of ganglion cells On the Cirrus SD-OCT, the GCL and the IPL are measured together as the ganglion cell layer complex (GCC Academia.edu is a platform for academics to share research papers

RNFL outcomes for CRION patient. Top left: Green circle indicates where the image was taken around the optic nerve head. Top right: the circular image around the ONH is flattened out and flipped 90 degrees so that all layers of the retina can be observed. The RNFL is being measured between the two red lines RNFL thickness is also shown to be a useful biomarker in Parkinson`s disease, where the amount of thinning correlates with disease severity and is an indicator for progression. A meta analysis of 13 studies concluded that the RNFL thickness of Parkinson`s patients is remarkably decreased compared to control group Pressure atrophy: One theory is that pressure too high for the back of the eye to withstand causes constriction of the blood flow with atrophy of the tissue (nerve fiber) supplied by that blood stream. They then atrophy and this is the basis for the thinning. Lowering the pressure below that threshold for damage prevents further blood vessel constriction and allows the remaining nerve fibers.

The RNFL deviation map appears clear, and the ONH/RNFL summary table and RNFL quadrant and clock hour analyses are all in the green. However, on careful evaluation of both the thickness maps and the RNFL TSNIT profile, it is clear that the superior RNFL is thinner than the inferior RNFL in the right eye peripapillary retinal nerve fiber layer (RNFL) and deformation of the optic nerve head [2-5]. The RNFL thickness of adult myopia is believed to become thinner with an increasing refractive degree of the eyes [3], while others believe that the average RNFL thickness decreases with increasing axial length [6]. Retinal structur RNFL average slopes (um/yr) Mean values significantly different from zero; GCC average slopes (um/yr) Trend Analysis - Clinical Utility; Trend Analysis - Fast Progressor RNFL Still Within Normal Limits! Trend Analysis - Clinical Utility; GCC and RNFL are Increasing! Look at the Scans! Other Pathology: Macula Edema; RNFL no change GCC.

RNFL thickness is considered to be a relevant parameter to infer axonal loss in patients with MS and/or ON. Although stipulated in numerous studies, the number of longitudinal studies and particularly those which investigated possible drug effects on the RNFL in MS is limited (6,7,21) RNFL is measure using optical coherence tomography (OCT) imaging. This imaging generate a picture of the back of the eye, known as the retina. An example is show below: In the first study involving Alzheimer's patients, researchers did an initial optical imaging and cognitive test of more than 30,000 UK residents and found that those with a. The RNFL can be assessed more precisely with OCT, which directly measures the thickness of the RNFL . Deep learning. Artificial intelligence (AI) is the intelligence exhibited by machines. In traditional computer programming, we write functions using manually coded rules. In contrast, machine learning (ML), a subfield of AI, relies on pattern. The RNFL Deviation Map shows deviation from normal. OCT en face fundus image shows boundaries of the cup and disc and the RNFL calculation circle. Neuro-retinal Rim Thickness profile is matched to normative data. RNFL TSNIT graph displays patient's RNFL measurement along the calculation circle, compared to normative data. RNFL Quadrant and Cloc

Lose RNFL -> creates RNFL wedges. What is the arrangement of neuro-retinal rim? Nerve fibers from periphery are closer to the optic disc edge and the fibers more proximal are closer to center of nerve. Which type of ganglion cells are more affected by glaucoma? M system because more periphera In the IT RNFL of the same eye, the slope is not significantly negative even though there is a real change in the RNFL on both the change profile and the raw OCT B-scan. Figure 2 also demonstrates false progression by trend-based analysis because of fluctuation in the ST RNFL thickness due to an epiretinal membrane Another longitudinal study of 279 glaucoma eyes reported that RNFL thickness, macular and ONH parameters decreased significantly faster in progressors versus non-progressors as determined by optic disc, RNFL and VF assessment.30 These studies indicate that the macular region is appropriate for detection of glaucoma progression; however, they.

(RNFL) and optic nerve head (ONH) parameters. RNFL thickness and ONH changes may reflect the changes that occur due to hypoxia in OSA. It was found that RNFL thinning was observed in OSA patients [20,21]. Theoreti-cally, the severity of OSA will result in thinner RNFL and ONH parameter changes based on the severity of the hy-poxia Conclusions: The thickest RNFL measurements were found in the inferior quadrant, followed by the superior, nasal, and temporal quadrants (ISNT rule applied to the RNFL). Thinner RNFL measurements were associated with older age and increasing myopia. Caucasians tend to have thinner RNFL values when compared with Hispanics and Asians

Retinal Nerve Fiber Layer Thickness - an overview

  1. The RNFL isn't the only form-birefringent structure in the eye. Anterior segment structures, such as the cornea, also phase-shift polarized light. So the latest instrument includes a compensating device or compensating corneal which is designed to remove the portion of the signal generated by the anterior segment
  2. LP248912-0 Retinal nerve fiber layer. The RNFL is formed from expansion of the fibers of the optic nerve and extends to the interior surface of the retina. The RNFL is divided into 4 quadrants when measured in each eye - temporal, superior, nasal, and inferior. Each 90 degree quadrant is further divided into three 30 degree sectors (clock hours)
  3. In myopic eyes, reproducibility of circumpapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer thickness measurement by optical coherence tomography showed excellent reproducibility except for the temporal quadrant RNFL thickness measurement.To evaluate the long-term reproducibility of circumpapillary retinal nerve fiber layer (RNFL) and macular ganglion.
  4. A repeatable 4µm or greater decrease in global RNFL thickness on two consecutive scans compared with baseline is considered a statistically significant change. 31 . Research shows global/average cpRNFL thickness is the most reproducible RNFL parameter and helpful in distinguishing normal patients from those with glaucoma. 3
  5. • The RNFL curve is drawn as a black line on a graph featuring thickness in microns and different areas of peripapillary RNFL. • The RNFL curve is drawn over a background of color coded areas representing RNFL thickness classification according to normative database. 20. RNFL analysis Circular scanning around ONH at a radius of 1. 73mm
  6. RNFL loss is 85% specific for glaucoma. RNFL defects follow an arcuate pattern, as would be expected from the normal RNFL anatomy. True RNFL defects are at least an arteriole in width and extend back to the optic disc compared with pseudo defects, which may be thin or may never extend to the optic nerve. 1-6,12,15,31-3
  7. OCT allows for measuring RNFL thickness as well as many features of the nerce (size, neuroretinal rim, etc) and also allows for macular scans that can be a piece to the puzzle when diagnosing and following progression of glaucoma. Visual field testing to look for the distinct visual field defects that are characteristic of glaucoma (including.

To evaluate the changes of retinal nerve fibre layer (RNFL) and ganglion cell layer/inner plexiform layer (GCL/IPL) with the severity of thyroid eye disease (TED). One hundred and forty-five eyes. • retinal nerve fiber layer (RNFL) thickness ar ound the optic nerve (peripapillary RNFL thickness) • Central retina and macula. • From a neurologic point of view, both types of imagi ng are important both to document the extent of optic neuropathy (RNFL thinning) and to exclude macular pathology as a cause for visual loss (macular imaging Draft Pick: WR Rashod Bateman, Minnesota - The idea of Bateman in Baltimore remains one of my favorite potential pairings for any player likely to be selected in the first round of the draft. Similar to Keenan Allen in my opinion, Bateman could become the go-to wide receiver the Ravens lacked last season

RNFL stands for Retinal Nerve Fiber Layer. Suggest new definition. This definition appears frequently and is found in the following Acronym Finder categories: Science, medicine, engineering, etc. See other definitions of RNFL. Other Resources: We have 1 other meaning of RNFL in our Acronym Attic The myelination follows the distribution of the axons, and is most commonly located near the optic nerve. Feathered, frayed borders can be seen that correspond to the shape and anatomical distribution of the ganglion cell axons. On rare occasion when the optic nerve has been injured, partial or total regression of the myelinated RNFL can be. To determine whether diffuse retinal nerve fiber layer (RNFL) defects, identified on red-free fundus photographs, could be identified on optical coherence tomography (OCT) en face structural images and to evaluate which factors are related to the different recognition patterns on en face images. This retrospective, cross-sectional study included open-angle glaucoma eyes with diffuse RNFL. The optic disc evaluation shows a cup to disc ratio of 0.4 OD and 0.5 OS. The visual field is normal OU, and the OCT shows a full RNFL OU. Advanced imaging technology may be better suited for distinguishing normal from pre-perimetric glaucoma or for following progression in mild or moderate glaucoma. It makes sense to use glaucoma imaging in. Average RNFL thickness indicates a patient's overall RNFL health. The mean value for RNFL thickness in the general population is 92.9 +/- 9.4 microns. Typically, a normal, nonglaucomatous eye has an RNFL thickness of 80 microns or greater. An eye with an average RNFL thickness of 70 to 79 is suspicious for glaucoma

Analysis of normal retinal nerve fiber layer thickness by

black holes (brain), brain lesions, copaxone, Dawson's fingers, MRI, OCT scan, optic neuropathy, RNFL (retinal nerve fiber layer), stopped taking injections, unchanging MRI 7 Comments 20 Dec 2012 To tell or not to tell, that is the questio Among RNFL scans, 20% contained artifacts (7 not evident on the final printout). Dr. Asrani and his colleagues have reported that in uveitic patients, RNFL parameters on OCT do not accurately reflect glaucoma severity. 4 During periods of active uveitis and elevated IOP, patients with uveitis-associated glaucoma had relatively normal RNFL. RNFL thinning in high myopes (Table 3) and this can be a clue to differentiate it from glaucomatous RNFL thinning. As we know glaucomatous optic nerve neuroretinal rim thinning has a characteristic pattern, inferior RNFL quadrant area is the most affected area. RNFL thickness generally follows ISNT rule (inferior > superior > nasal > temporal) rNFL prides itself on being a bellwether of reddit design in many ways. We, through no fault of our own, were notorious for crashing the site in earlier years thanks to the success of game threads. The Super Bowl was a guaranteed downtime for the entire site for quite some time. Our CSS implementation pushed the boundaries of what subs could do. An OCT-based correspondence map, which correlated VF areas with peripapillary RNFL sectors was created to evaluate the relationship between glaucomatous RNFL thinning and VF loss in six nerve.

RNFL Thickness Map - EyeCareP

RNFL analysis on average RNFL thickness obtained borderline thinning in the right eye and significant thinning in the left eye. Hemifield and quadrant RNFL thickness appear to be thinning in the Inferior, Superior, and Nasal regions of the right and left eye according to the ISNT rule typical of glaucoma Myopia is a major public health problem that is growing worldwide [].Many studies have investigated structural changes in myopic eyes, mainly the thinning of the peripapillary retinal nerve fiber layer (RNFL) and deformation of the optic nerve head [2,3,4,5].The RNFL thickness of adult myopia is believed to become thinner with an increasing refractive degree of the eyes [], while others. Meaning. RNFL. Retinal Nerve Fiber Layer. RNfL. Real Nappies for London (UK) RNFL. Retinal Nerve Fiber Layer Defect (ophthalmology) Note: We have 1 other definition for RNFL in our Acronym Attic. new search

Study to Assess OCT: RNFL and GCL in MS Patients The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government Glaucoma is a progressive vision condition that can lead to permanent blindness. Learn more about the types, causes, symptoms, risk factors, diagnosis, and treatment of glaucoma

Average RNFL Thickness - EyeCareP

and RNFL. The appearance of the optic disc was not used as an exclusion criterion . no disc hemorrhage, RNFL defects: normal appearance of optic disc - 2 examiners. Visual Field. normal Humphrey. The RNFL wedge defect can be observed as a dip in the RNFL TSNIT plot, in the circumpapillary B-scan, and as Borderline in the superior quadrant of the ISNT analysis (Fig. 3, red arrows). The 4.1 mm and 4.7 mm RNFL circle scans confirm the presence and extent of this wedge defect (Fig. 4A, B, C) What is the full form of RNFL, What does RNFL stand for? Abbreviation

Elevated-Tension Open-Angle Glaucoma; Moderate Damage

Monitoring Glaucoma Progression with OC

3.5 mm, 4.1 mm and 4.7 mm RNFL scans • RNFL thickness decreases as distance from BMO margin increases • Slope of this decrease over time may provide very useful information about progressive loss of RNFL Rate of RNFL loss may be faster or slower depending on distance from BMO margin The combination of RNFL thickness from three differen loss of RNFL can be seen as a wedge of diminished light reflection. This is best appreciated with a red-free (green or blue) filter. However, early glaucoma RNFL loss often appears as subtle attenuation of the light reflection and can be difficult to detect. Visual field Glaucomatous visual field defects include an early paracentral scotoma RNFL deviation map is a useful tool for evaluating glaucoma regardless of localized or diffuse defect type and has advantages over circumpapillary RNFL measurement for detecting localized RNFL defects. Purpose . To evaluate the diagnostic ability of the retinal nerve fiber layer (RNFL) deviation map for glaucoma with localized or diffuse RNFL. RNFL thickness is within (green) or above (white) normal limits. (B) 3.4mm diameter circle showing RNFL thickness is within or above normal limits. (C) Significance plot showing that RNFL thickness is borderline (yellow) at a few grid locations near the disc, but within normal limits (clear) for all other locations

RNFL Optometry Abbreviation Meaning - All Acronym

global and local RNFL thinning (mm/year) in each group. Details of the use of these models for assessment of longitudinal changes in glaucoma have been described.19,20,25 In brief, models were first t with RNFL thickness measurements as a response variable, whereas time, group, and a timeegroup interaction were defined as fixed effects Timothy D McGarity, M.D. Aug 05, 2013. Average RNFL thickness is determined differently on each machine and will be validated on subsequent test (snap shot). People who have asymmetry or thinning of their rnfl may be susceptible. Severe myopia may thin the rnfl, but not much. Best wishes RNFL from binary OCT image after detection of boundaries of RNFL. The RNFL is the first layer in OCT image, therefore implemented algorithm process OCT image from top to bottom. If it finds white pixels or white line that indicates upper layer of RNFL and the process continues until another white line is detected

Nutritional Optic Neuropathy

The RNFL 3.45 protocol identifies the RNFL thickness of the peripapillary area by performing circular scans with a diameter of 3.45 mm around the optic disc. What is important here is the sum of four 1024-A scans performed in 0.15 s, that is, the data of 4096 scans in total. The RNFL output is divided into three sections Results The average RNFL thickness and the thickness of each of the 90° quadrants were significantly thinner in people with epilepsy than healthy controls (p<0.001, t test). In a multivariate logistic regression model, drug resistance was the only significant predictor of abnormal RNFL thinning (OR=2.09, 95% CI 1.09 to 4.01, p=0.03) •RNFL thickness •Comparison of numerical data -natural course of a disease -response to therapy. Macular Map Thickness data Thickness - Topographic and Comparison to normal -Traffic light . Macular Map •Volume, cube, thickness maps •Immediate visualization of increased or decrease RNFL thickness measures should not be relied upon if scan quality is low. In addition, the high reflectance of blood vessels can cause the automated segmentation to miscalculate RNFL thickness measures, often making the RNFL appear thinner around the major blood vessels. The accuracy of the automated segmentation should be checked for each scan.